Publications by authors named "T Chiarabini"

Background: Trichophyton mentagrophytes ITS genotype VII (TMVII) has recently been identified in France as the causative agent of dermatophyte infections transmitted during sexual activity among men who have sex with men (MSM).

Objectives: Our objective was to provide new insights into the epidemiology, clinical presentation and treatment of TMVII infections based on cases diagnosed from October 2022 to September 2023 in three medical mycology laboratories in Paris. Additionally, we aimed to perform molecular characterization of TMVII strains collected in Paris, as well as in Switzerland.

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Article Synopsis
  • The CORIPLASM trial aimed to assess whether covid-19 convalescent plasma is effective in treating hospitalized adults with moderate covid-19, including those with weakened immune systems.
  • Conducted across 19 hospitals in France, the trial included 120 participants randomly assigned to receive either convalescent plasma or usual care between April 2020 and April 2021.
  • Key outcomes measured included the proportion of patients experiencing worsening symptoms by day 4 and survival without needing assisted ventilation by day 14, while secondary outcomes assessed overall survival and recovery times.
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HIV post- exposure prophylaxis (PEP) is a prevention tool for individuals with a recent potential exposure to HIV. Doravirine has been available since 2019 in combination with tenofovir disoproxil fumarate and lamivudine and has not been evaluated as a PEP. DOR/3TC/TDF is our department's most commonly prescribed PEP treatment since 2021.

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Transmission of dermatophytes, especially Trichophyton mentagrophytes genotype VII, during sexual intercourse has been recently reported. We report 13 such cases in France. All patients were male; 12 were men who have sex with men.

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