Publications by authors named "T Ceylan"
Article Synopsis
- The study aimed to examine the protective effects of Thymoquinone (THQ) against testicular damage induced by Methotrexate (MTX) in rats.
- The experiment involved five groups and included sperm analysis, histopathology, and biochemical tests to assess the impact on testicular health.
- Results showed that THQ significantly improved sperm quality and testicular function parameters, indicating its potential role in mitigating infertility caused by chemotherapy.
Effect of vitamin B12 on methotrexate-induced cardiotoxicity in rats.
Iran J Basic Med Sci
January 2024
Article Synopsis
- - This study investigates the cardiotoxic effects of methotrexate (MTX), a chemotherapy drug, and the potential protective role of vitamin B12 in mitigating this toxicity in rats.
- - Rats were divided into four groups: a control group, a vitamin B12 group, an MTX group, and a combined MTX and vitamin B12 group, with various biomarkers and tissue expressions evaluated to assess heart health.
- - The results showed MTX caused significant negative changes in heart-related factors and that vitamin B12 effectively normalized these changes, emphasizing the importance of vitamin B12 supplementation during MTX treatment.
The aim of this study was the investigation of basic motor skills in 5-14-year-old boys and girls. A total of 842 primary school children, 421 boys and 421 girls, participated in the study. 13.
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- * The study involved administering NP and TQ to different rat groups to evaluate the effects on brain health and behavior, using various tests and tissue evaluations.
- * Results indicated that NP caused significant brain damage and behavioral issues, but TQ treatment improved these conditions by reducing neuron degeneration and oxidative stress markers.
Article Synopsis
- Pseudoephedrine (PSE), a common ingredient in cold medications, is widely used by pregnant women to treat colds, with one in four expecting mothers using it.
- A study was conducted on pregnant rats to analyze the impact of various doses of PSE on fetal long bone development through measurements of weights, heights, and bone ossification after cesarean delivery.
- Results showed a decrease in morphometric data, ossification rates, and calcium levels in bones with increasing PSE doses, indicating that PSE usage during pregnancy negatively affects fetal bone growth.