Publications by authors named "T Cerdo"
Article Synopsis
- The study investigated the inflammatory profiles of Rheumatoid Arthritis (RA) patients to identify those at higher risk for cardiovascular (CV) issues and evaluated the effects of specific medications.
- Researchers analyzed data from 387 RA patients, dividing them into groups based on prior CV events and treatment with disease-modifying drugs, while examining various inflammatory biomarkers.
- Findings revealed three distinct RA patient groups with varying inflammatory levels and CV risks, highlighting that certain treatments effectively lowered disease activity and improved inflammatory markers associated with CV risk, suggesting a pathway for personalized management in RA care.
APS patients exhibit a wide clinical heterogeneity in terms of the disease's origin and progression. This diversity can be attributed to consistent aPL profiles and other genetic and acquired risk factors. Therefore, understanding the pathophysiology of APS requires the identification of specific molecular signatures that can explain the pro-atherosclerotic, pro-thrombotic and inflammatory states observed in this autoimmune disorder.
View Article and Find Full Text PDFGut microbiota has been linked to infant neurodevelopment. Here, an association between infant composite cognition and gut microbiota composition is established as soon as 6 months. Higher diversity and evenness characterize microbial communities of infants with composite cognition above (Inf-aboveCC) versus below (Inf-belowCC) median values.
View Article and Find Full Text PDFArticle Synopsis
- The prenatal and early postnatal periods are crucial for brain and gut microbiota development, with nutrition playing a key role in influencing these changes.
- The relationship between gut microbiota and the brain, known as the microbiota-gut-brain axis (MGBA), has led to increased interest in how nutritional interventions during these times might affect neurodevelopmental outcomes.
- Current research suggests that specific nutrients could positively impact the MGBA, potentially preventing or treating neuropsychiatric disorders and highlighting the need for personalized nutrition strategies throughout early life stages.