Publications by authors named "T Carvalho"
Objectives: The aim of the study was to investigate the caries-preventive effect of fluoride-free toothpastes, containing either herbal agents or (nano-)hydroxyapatite.
Methods: Bovine dentin specimens each having a sound [ST], and a demineralized area [DT]) were prepared and randomly allocated to eleven groups (n=187). Treatments during pH-cycling (28 days;6x120min demineralization/day) were brushing 2x/day with: 0ppm F- [NaF0], 500ppm F- [NaF500], 1,100ppm F- [NaF1100], grape seed extract [GSE], (nano-)hydroxyapatite [nHA, HA], melaleuca oil [MO1, MO2, MO-CU] and propolis + myrrh [PM1, PM2] containing dentifrices.
Paving the way for the use of Statherin-Derived Peptide (StN15) to control caries through acquired pellicle and biofilm microbiome engineering: Proof-of-concept in vitro/in vivo studies.
Arch Oral Biol
December 2024
Objective: This proof-of-concept sequence of in vivo/in vitro studies aimed to unveil the role of acquired enamel pellicle (AEP) engineering with statherin-derived peptide (StN15) on the AEP protein profile, enamel biofilm microbiome in vivo and on enamel demineralization in vitro.
Design: In vivo studies, 10 volunteers, in 2 independent experiments (2 days each), rinsed (10 mL,1 min) with: deionized water (negative control) or 1.88 × 10 M StN15.
Objectives: Detecting premalignant lesions for pancreatic ductal adenocarcinoma, mainly pancreatic intraepithelial neoplasia (PanIN), is critical for early diagnosis and for understanding PanIN biology. Based on PanIN's histology, we hypothesized that diffusion tensor imaging (DTI) and T2* could detect PanIN.
Materials And Methods: DTI was explored for the detection and characterization of PanIN in genetically engineered mice (KC, KPC).
Article Synopsis
- Male frogs use specific calls to attract mates and avoid competition, with their call characteristics influenced by their size and environment.
- The acoustic adaptation hypothesis suggests that frogs evolve their calls to improve their reach and clarity in their habitats.
- Research on Neotropical treefrogs revealed a significant relationship between body size and call frequency, but did not support the AAH claims linking calls to environmental factors, suggesting other influences like female choice may play a role.