Within-host dynamics and random duration of pathogen infection: Implications for between-host transmission.

Taking an ecological perspective, this paper reports theoretical and empirical results concerning fatal bacterial infections of adult insects. Two models, each combining deterministic and stochastic elements, characterize how the pathogen's dynamics might govern an infected host's mortality rate. We analyze the models in detail for exponential pathogen growth, and apply them to observed insect mortality when the pathogen's growth is unregulated.

Pathogen transmission at stage-structured infectious patches: Killers and vaccinators.

Spatial localization of an obligate-killing, free-living pathogen generates a landscape of patches where new infections occur. As an infectious patch ages, both pathogen exposure at the patch and the probability of lethal infection following exposure can decline. We model stage-structured infectious patches, where non-lethal exposure can naturally "vaccinate" susceptible hosts.

Assortative Mating: Encounter-Network Topology and the Evolution of Attractiveness.

We model a social-encounter network where linked nodes match for reproduction in a manner depending probabilistically on each node's attractiveness. The developed model reveals that increasing either the network's mean degree or the "choosiness" exercised during pair formation increases the strength of positive assortative mating. That is, we note that attractiveness is correlated among mated nodes.

Spatial Competition: Roughening of an Experimental Interface.

Limited dispersal distance generates spatial aggregation. Intraspecific interactions are then concentrated within clusters, and between-species interactions occur near cluster boundaries. Spread of a locally dispersing invader can become motion of an interface between the invading and resident species, and spatial competition will produce variation in the extent of invasive advance along the interface.

Environmentally transmitted parasites: Host-jumping in a heterogeneous environment.

Groups of chronically infected reservoir-hosts contaminate resource patches by shedding a parasite׳s free-living stage. Novel-host groups visit the same patches, where they are exposed to infection. We treat arrival at patches, levels of parasite deposition, and infection of the novel host as stochastic processes, and derive the expected time elapsing until a host-jump (initial infection of a novel host) occurs.