Publications by authors named "T Canto-Cetina"
Association between personality traits, eating behaviors, and the genetic polymorphisms -rs9939609 and 30 bp u-VNTR with obesity in Mexican Mayan children.
Front Genet
July 2024
Introduction: Genetic variants that control dopamine have been associated with obesity in children through loss of control of satiety and impulses, the manifestation of addictive eating behaviors, and specific personality traits. The variants include -rs9939609 and the 30 pb u-VNTR low-transcription alleles (LTA).
Objective: To evaluate the genetic association of -rs9939609 and the LTA, along with personality traits and eating behavior with obesity in Mayan children from Mexico.
Article Synopsis
- The study investigated the relationship between two genetic polymorphisms, rs3480 and rs16835198, in the FNDC5 gene and their association with type 2 diabetes mellitus (T2DM) in Maya-Mestizo women.
- The research involved 547 postmenopausal women, using DNA from blood samples and real-time polymerase chain reaction to analyze the polymorphisms.
- Results indicated that the G-allele of rs3480 and a specific haplotype were significantly linked to a higher risk of T2DM in this population, suggesting a potential genetic factor in the disease's development.
Objective: This study aimed to analyze the association between rs3480 and rs16835198 of and their haplotypes with variations in bone mineral density (BMD) and osteopenia/osteoporosis in postmenopausal Mayan-Mestizo women.
Methods: We studied 547 postmenopausal women of Maya-Mestizo origin. BMD was measured in the lumbar spine and total hip by dual-energy X-ray absorptiometry.
Background: Obesity protects against bone loss, but it increases the risk of fragility fractures.
Aim: To determine if bone mineral density (BMD) and the prevalence of fractures are different in postmenopausal Maya-Mestizo women grouped according to their body mass index (BMI).
Subjects And Methods: We studied 600 postmenopausal Maya-Mestizo women.
Genetic variation of FTO: rs1421085 T>C, rs8057044 G>A, rs9939609 T>A, and copy number (CNV) in Mexican Mayan school-aged children with obesity/overweight and with normal weight.
Am J Hum Biol
January 2019
Objectives: Genetic variation of the fat mass and obesity associated gene (FTO) has been identified as a risk factor for obesity and obesity traits. Distribution of FTO single nutleotide polymorphisms (SNPs) rs1421085T>C, rs9939609T>A, rs8057044G>A and copy number variation (CNV) was evaluated in association with childhood obesity or overweight status in children with Mayan ethnicity.
Methods: We included 318 school-aged children with obesity or overweight status (body mass index [BMI]: >85th percentile) and 303 children with normal weight (BMI: 15th-85th percentile).