Publications by authors named "T Calverley"

Article Synopsis
  • Hypoxia, which is lower oxygen levels, can negatively affect cognitive functions, particularly impacting memory while leaving attention tasks relatively untouched.
  • In a study with 12 male participants, cognitive performance was tested after varying periods of hypoxic exposure, revealing decreased oxygen delivery to brain regions involved in memory tasks.
  • The results indicate that cognitive performance varies across domains, with memory showing significant impairment due to hypoxia, while tasks related to selective attention and response inhibition remain resilient.
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New Findings: What is the central question of this study? What are the molecular, cerebrovascular and cognitive biomarkers of retired rugby union players with concussion history? What is the main finding and its importance? Retired rugby players compared with matched controls exhibited lower systemic nitric oxide bioavailability accompanied by lower middle cerebral artery velocity and mild cognitive impairment. Retired rugby players are more susceptible to accelerated cognitive decline.

Abstract: Following retirement from sport, the chronic consequences of prior-recurrent contact are evident and retired rugby union players may be especially prone to accelerated cognitive decline.

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Article Synopsis
  • High-intensity interval training (HIIT) is found to be a more time-efficient workout compared to moderate-intensity steady-state exercise (MISS), but its effects on free radicals and coagulation are unclear.
  • In a study with 16 healthy males, participants were divided into HIIT and MISS groups to analyze blood samples for free radicals and clotting factors before and after exercise.
  • The results showed that submaximal MISS led to greater increases in free radicals and clotting measures than HIIT, suggesting that HIIT may be safer and more beneficial for vascular health.
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Article Synopsis
  • - The study examines how continuous hypoxia affects cerebral shear rate, endothelial function, and cerebral oxygen delivery (CDO) in healthy males, comparing results from normoxia (normal oxygen levels) and hypoxia (reduced oxygen levels).
  • - Results showed that while systemic blood flow (brachial artery) decreased during hypoxia, the cerebral blood flow regulation remained intact, even with reduced shear rate and oxygen delivery in the internal carotid artery.
  • - The findings suggest that the negative impact of continuous hypoxia on oxygen delivery is independent of cerebral endothelial function, contrasting with effects seen during cyclic intermittent hypoxia, indicating that the effects depend on the duration and nature of the hypoxia exposure.
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Nihonium (Nh, element 113) and flerovium (Fl, element 114) are the first superheavy elements in which the shell is occupied. High volatility and inertness were predicted for Fl due to the strong relativistic stabilization of the closed sub-shell, which originates from a large spin-orbit splitting between the and orbitals. One unpaired electron in the outermost sub-shell in Nh is expected to give rise to a higher chemical reactivity.

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