Methodology of cfHPV-DNA Detection in Head and Neck Cancer: A Systematic Review and Meta-analysis.

Objective: We aim to compare the diagnostic accuracy of the different methodologies used in the detection of cell-free human papillomavirus (HPV) DNA in HPV-associated head and neck squamous cell carcinoma detection using bivariate analysis methods.

Data Sources: Pubmed, Embase, and Scopus were queried using a broad search strategy to search for relevant studies.

Review Methods: Test characteristics were extracted from 33 studies following literature screening, and underwent analyses utilizing a bivariate approach.

Persistent organochlorine pollutants in different bivalve species from central Vietnamese coasts: Concentrations, profiles, and biota-sediment accumulation factors.

Concentrations of typical persistent organochlorine pollutants (POCPs) like organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in five bivalve species collected from central Vietnamese coasts were determined to provide insights into spatial distribution and bioaccumulation characteristics of these substances. Concentrations of pollutants decreased in the order: PCBs (median 14.6; range 1.

Functional and radiological sinonasal outcomes of CFTR modulators for sinus disease in cystic fibrosis: A meta-analysis.

Background: Cystic fibrosis transmembrane conductance regulator (CFTR) modulators improve pulmonary outcomes in cystic fibrosis (CF) by stabilizing the CFTR protein on respiratory epithelial surfaces. To determine the efficacy of CFTR modulators on sinonasal outcomes in patients with CF, we performed a meta-analysis of clinical trials to date that include functional and radiographic evidence of sinus disease.

Methods: English full-text articles were searched in PubMed, Embase, and Scopus databases.

Machine Learning Methods in Classification of Prolonged Radiation Therapy in Oropharyngeal Cancer: National Cancer Database.

Objective: To investigate the accuracy of machine learning (ML) algorithms in stratifying risk of prolonged radiation treatment duration (RTD), defined as greater than 50 days, for patients with oropharyngeal squamous cell carcinoma (OPSCC).

Study Design: Retrospective cohort study.

Setting: National Cancer Database (NCDB).