Publications by authors named "T C L Franca"
Use of the transposition u-shaped palatal flap and polypropylene mesh to correct oronasal communication after resection of maxillary osteosarcoma in a dog.
Braz J Vet Med
November 2024
Although less common in the axial skeleton, osteosarcoma, when present in the facial bones, can generally require invasive surgical procedures, which require large resections followed by reconstructions that can disfigure the patient and predispose them to physiological difficulties. We describe a technique used to correct oronasal communication that occurred after suture dehiscence from a left central hemimaxillectomy procedure in a female Rottweiler diagnosed with osteosarcoma. Clinical and radiographic findings are discussed, as well as the palatal mucosal flap surgical technique associated with the use of a synthetic polypropylene mesh.
View Article and Find Full Text PDFScholarly publishing has been shaped by the pressure of a liquid economy to become an exercise in branding more than a vehicle for the advancement of science. The current revolution in artificial intelligence (AI) is poised to make matters worse. The new generation of large language models (LLMs) have shown impressive capabilities in text generation and are already being used to write papers, grants, peer review reports, code for analyses, and even perform literature reviews.
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- ISG15 deficiency is a rare inherited syndrome that leads to frequent infections by less harmful mycobacteria and interferon-related issues, and this study focuses on two unrelated Brazilian patients sharing the same genetic mutation in the ISG15 gene.
- Assessments revealed both patients had low production of IFN-γ and distinct clinical symptoms, impacting their immune response and leading to both infectious and neurological manifestations.
- The researchers identified a specific mutation (c.83 T > A) that destabilizes the ISG15 protein, along with a significant number of differentially expressed genes linked to immune pathways, marking the first documentation of these cases in Brazil.
Artificial insemination (AI) success in bovine reproduction is vital for the cattle industry's economic sustainability and for advancing the understanding of reproductive physiology. Identify high-fertile animals' fertility is a complex task due to multifactorial traits, including hormonal, age-related, and body condition factors. Early high-fertility identification is crucial for timely interventions and enhancing AI success.
View Article and Find Full Text PDFHydroalcoholic extract of Araucaria sp. brown propolis alleviates ulcerative colitis induced by TNBS in rats by reducing inflammatory cell infiltration and oxidative damage.
J Pharm Pharmacol
October 2024
Objective: To investigate the effects of Araucaria sp. brown propolis (ABP) against trinitrobenzenesulfonic acid (TNBS)-induced colitis in rats.
Methods: Animals received vehicle (1% DMSO, 1 ml/kg) or hydroalcoholic extract of ABP (hydroalcoholic extract of Araucaria sp.