Publications by authors named "T C Dan"
Objective: To analyze part of the mechanism of electroacupuncture on Sishencong (EX-HN1) for stroke-related sleep disorders (SSD) and post-stroke cognitive impairment (PSCI).
Methods: Using a randomized controlled trial (RCT) design, 72 patients were assigned to the electro-acupuncture (EA) group or the sham acupuncture (SA) group. A healthy control (HC) group was also included.
Article Synopsis
- The IHCNP study was an 18-month observational research focused on patients with mild cognitive impairment (MCI) post-ischemic stroke in Romania.
- The analysis involved 100 patients who underwent various cognitive assessments at baseline and follow-ups to track changes over time.
- Results showed significant cognitive decline by the end of the study, emphasizing the necessity for early diagnosis and continuous monitoring to better manage MCI progression in post-stroke patients.
Exploratory Evaluation of Personalized Ultrafractionated Stereotactic Adaptive Radiation Therapy (PULSAR) With Central Nervous System-Active Drugs in Brain Metastases Treatment.
Int J Radiat Oncol Biol Phys
November 2024
Purpose: Brain metastases (BMs) affect an increasing number of cancer patients and are typically managed with stereotactic radiosurgery (SRS). Our institution advocates the use of Personalized Ultrafractionated Stereotactic Adaptive Radiation Therapy (PULSAR), where radiation is delivered in high-dose pulses at extended intervals allowing for treatment adaptation and easy concurrent systemic therapy integration. We explore the integration of PULSAR with central nervous system (CNS)-active drugs (CNS-aDs).
View Article and Find Full Text PDFArticle Synopsis
- This study focused on developing a multiomics approach that combines radiomics, dosiomics, and delta features to predict treatment responses in brain metastasis (BM) patients receiving PULSAR therapy.
- Using data from 39 BM patients and 69 lesions, the researchers evaluated multiple models to categorize lesions based on a volume reduction of over 20% post-treatment, finding that their ensemble feature selection (EFS) model significantly outperformed individual models.
- The EFS model achieved high performance metrics, including an AUC of 0.979 and accuracy of 0.917, showcasing the potential of this integrated approach for better patient management and treatment optimization in BM cases.
Streptococcus thermophilus (S. thermophilus) is a widely used starter culture in dairy fermentation, but most strains are galactose-negative and only metabolize glucose from lactose hydrolysis. In this study, we aimed to uncover the mechanisms underlying the acquisition of a stable galactose-positive (Gal) phenotype in a mutant strain of S.
View Article and Find Full Text PDF