Publications by authors named "T C Crul"
Purpose: The aims of this study were to explore (1) the considerations of people with spinal cord injury (SCI) in choosing to use non-pharmacological treatments (N-PTs) for neuropathic pain (NP), (2) which factors influence their decision and who is involved in this choice.
Materials And Methods: Eleven individuals with SCI and NP were interviewed. Interviews were transcribed verbatim, transcripts were analysed through thematic coding, following an inductive content analysis approach.
Context/objective: Chronic pain is a common secondary condition in spinal cord injury (SCI). Pharmacological interventions to reduce pain are associated with side effects. The reported effects of non-pharmacological treatments are unclear.
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- * There are currently no targeted treatments for either RAP or early CP, making it important to explore the underlying cell interactions that lead to disease progression.
- * This study found that inhibiting Orai1, a key signaling mechanism linked to calcium overload in pancreatic cells, can halt the progression of RAP and early CP, suggesting that targeting Orai1 might help prevent severe stages of CP.
Background And Aims: Thiopurine-induced acute pancreatitis (TIP) is one of the most common adverse events among inflammatory bowel disease patients treated with azathioprine (AZA), representing a significant clinical burden. Previous studies focused on immune-mediated processes, however, the exact pathomechanism of TIP is essentially unclear.
Methods: To model TIP in vivo, we triggered cerulein-induced experimental pancreatitis in mice receiving a daily oral dose of 1.
Objective: To describe the prevalence and characteristics of spinal cord injury (SCI)-related pain during initial inpatient rehabilitation and to investigate relationships with demographic and lesion characteristics.
Design: Cohort during inpatient rehabilitation.
Setting: Eight specialized SCI rehabilitation centers in the Netherlands.