Publications by authors named "T Buronfosse"
Article Synopsis
- Dairy cattle breeds face recurrent recessive genetic defects that are often undetected due to conventional observation techniques missing various conditions, particularly those without clear symptoms.
- A new data mining framework has been developed to identify these hidden recessive defects in livestock by analyzing genomic data and comparing homozygote numbers in cattle with diverse life histories.
- This research uncovered 33 new genetic loci linked to increased juvenile mortality, offering insights into the genetic causes of inbreeding depression, which can enhance animal welfare and reduce industry losses.
Article Synopsis
- The study investigates how hyperadrenocorticism (HAC) affects calcium and phosphate metabolism in dogs, linking these changes to kidney health.
- It compares 54 dogs across three groups: those with HAC, those with other illnesses, and healthy dogs, measuring various serum and urinary biomarkers.
- Results show that dogs with HAC have significantly higher serum phosphate levels, urinary calcium excretion, and altered Vitamin D metabolism, suggesting a connection between HAC, proteinuria, and kidney function.
Background: In a previous study, telmisartan suppressed aldosterone secretion in healthy cats but not in cats with primary hyperaldosteronism (PHA).
Hypotheses: Telmisartan suppresses aldosterone secretion in middle-aged healthy cat and cats with diseases that may result in secondary hyperaldosteronism, but not in those with PHA.
Animals: Thirty-eight cats: 5 with PHA; 16 with chronic kidney disease (CKD), subclassified as hypertensive (CKD-H) or non-hypertensive (CKD-NH); 9 with hyperthyroidism (HTH); 2 with idiopathic systemic arterial hypertension (ISH); and 6 healthy middle-aged cats.
Glioblastoma is considered the most common malignant primary tumor of central nervous system. In spite of the current standard and multimodal treatment, the prognosis of glioblastoma is poor. For this reason, new therapeutic approaches need to be developed to improve the survival time of the glioblastoma patient.
View Article and Find Full Text PDFObjective: To compare progesterone (P4) concentrations measured with surface plasmon field-enhanced fluorescence spectroscopy (SPFS) and chemiluminescence immunoassay (CLIA) in serum and plasma samples of client-owned bitches of various ages and breeds and to determine reference ranges for P4 concentrations at various stages of the estrous cycle.
Samples: 102 serum samples and 104 plasma samples.
Procedures: In experiment 1, 1 aliquot each of serum and plasma was analyzed for P4 concentration by use of SPFS incorporated in a veterinary-specific point-of-care immunologic analyzer and CLIA.