[The concentration of lactate in amniotic fluid in delivery under physiological course of pregnancy].

The study was carried out to establish admissible range of concentrations of lactate using standard biochemical method in amniotic fluid at first period of delivery under physiologically progressing pregnancy. The sampling included 44 women examined during first period of urgent delivery. The samples of amniotic fluid were taken during the first period of delivery using vaginal amnitomy.

[Metabolic and genetic predictors of restenosis and thrombosis of arterial bioprostheses in the femoropopliteal position].

The present study was aimed at analysing the role of certain cytokines in the development of restenosis and thrombosis of biological prostheses "KemAngioprosthesis", as well as assessing the effect of polymorphic variants of genes on expression of pro- and anti-inflammatory interleukins. Group One (n=52) was composed of patients with an unfavourable outcome (prosthesis restenosis, accompanied by thrombosis in 35 patients). Group Two (n=59) comprised patients with functioning and unaltered prostheses.

Assessment of current exposure levels in different population groups of the Kola Peninsula.

Activity concentrations of 137Cs and 90Sr in samples of vegetation and natural food products collected in the Kola Peninsula in 1998 and 1999 indicate a very slow decrease in contamination levels during the last decade, mainly due to the physical decay of the radionuclides. The activity concentrations of 137Cs in reindeer meat decreased with a half-life of about 9 years. 137Cs in lichen, moss and fungi is significantly higher than in natural vegetation (grasses) and agricultural plants (potatoes).

[The toxicological characteristics of ammonium glycyrrhizinate (glycyram). A study of its acute and subacute toxicity].

A single parenteral and oral administration of ammonium glycyrrhizinate in rat and mice experiments showed that the compound is related to practically nontoxic drugs. Its repeated administration (30 times) into the stomach in a maximum daily therapeutic dose (7 mg/kg) and in a four-fold dose (28 mg/kg) did not cause signs of intoxication, essential changes in the hematological and integral parameters, shifts in the activity of serum enzymes, morphological changes in the cell structures of the internal organs. Administration of the drug in a dose of 28 mg/kg for a second time led to changes in the activity of some enzymes in the brain, the development of parenchymatous dystrophy of the liver which changed to acidophilic necrosis attended with signs of regeneration.

[Experimental research on the chronic inhalational toxicity of chloracetophon].

The chronic inhalational toxicity of chloracetophon was studied on 24 albino Wistar rats, with concentrations 20 mg X m-3. The animal were exposed 4 hours/daily, 5 days/weekly, for 90 days. Integral, biochemical, histological and electron-microscopic methods were used for the evaluation of the toxic effect of the preparation.