Publications by authors named "T Burkard"

Article Synopsis
  • The study examined the relationship between smoking habits and brain health in patients with atrial fibrillation (AF), focusing on brain lesions and volumes using MRI scans.
  • A total of 1,728 patients were analyzed, revealing that heavy smoking and longer smoking duration were linked to reduced gray matter volume and increased risk of white matter lesions (WMLs).
  • Additionally, patients who quit smoking for at least 16 years had fewer small noncortical infarcts and smaller WML volumes, indicating that long-term cessation may improve brain health.
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Introduction: Iron overloading disorders are associated with decreased bone mineral density. However, evidence on fracture risk is scarce. Therefore, we evaluated the risk of fracture associated with iron overload disorders, compared to matched controls.

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Background: The World Health Organisation (WHO) has identified a range of symptomatic manifestations to aid in the clinical diagnosis of post-COVID conditions, herein referred to as post-acute COVID-19 symptoms. We conducted an international network cohort study to estimate the burden of these symptoms in North American, European, and Asian populations.

Methods: A federated analysis was conducted including 10 databases from the United Kingdom, Netherlands, Norway, Estonia, Spain, France, South Korea, and the United States, between September 1st 2020 and latest data availability (which varied from December 31st 2021 to February 28th 2023), covering primary and secondary care, nationwide registries, and claims data, all mapped to the Observational Medical Outcomes Partnership Common Data Model (OMOP CDM).

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Objectives: In this multi-center study, we proposed a structured reporting (SR) framework for non-small cell lung cancer (NSCLC) and developed a software-assisted tool to automatically translate image-based findings and annotations into TNM classifications. The aim of this study was to validate the software-assisted SR tool for NSCLC, assess its potential clinical impact in a proof-of-concept study, and evaluate current reporting standards in participating institutions.

Methods: A framework for SR and staging of NSCLC was developed in a multi-center collaboration.

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