Differentiating neoplastic from non-neoplastic spinal cord pathologies may be challenging due to overlapping clinical and radiological features. Spinal cord tumors, which comprise only 2-4% of central nervous system tumors, are rarer than non-tumoral myelopathies of inflammatory, vascular, or infectious origins. The risk of neurological deterioration and the high rate of false negatives or misdiagnoses associated with spinal cord biopsies require a cautious approach.
View Article and Find Full Text PDFBackground: Rodent models are commonly used experimentally to assess treatment effectiveness in spinal fusion. Certain factors are associated with better fusion rates. The objectives of the present study were to report the protocols most frequently used, to evaluate factors known to positively influence fusion rate, and to identify new factors.
View Article and Find Full Text PDFFor patients with locally advanced non-small cell lung cancer invading the spine, induction chemoradiotherapy combined with radical en bloc resection is the key to obtaining long-term survival. With time, our operative technique evolved to a two-step surgery as we experienced numerous perioperative complications during one step surgery. The aim of our study was to assess postoperative morbimortality and long-term survival of both techniques.
View Article and Find Full Text PDFBackground: Regarding their relation to the spinal cord (SC), resection of pre-medullary meningiomas may be technically challenging. Anterior approach via corpectomy represents a nice option reducing the need for mobilization of the SC.
Case Description: We describe the case of a patient presenting with a cervical meningioma, located anterior to the SC and operated on through an anterior approach.