Publications by authors named "T Brett Reece"
Background: The clinical significance of natural and treatment-emergent antibodies specific for amustaline/glutathione pathogen-reduced red blood cells (PRRBCs) is not known.
Study Design And Methods: A Phase 3, randomized clinical trial of PRRBCs (ReCePI) compared PRRBCs with conventional RBCs in cardiac or thoracic-aorta surgery. Subjects transfused during and for 7 days after surgery were screened for PRRBC-specific antibodies at baseline, 28 and 75 days post-surgery.
Article Synopsis
- Heart and lung transplantation are important treatments for severe heart and lung failure, but there's a shortage of donor organs, prompting interest in thoracoabdominal normothermic regional perfusion (TA-NRP) to enhance organ availability from circulatory death donors.
- A study evaluated a single-center TA-NRP program, highlighting essential processes and challenges in its adoption, noting an average TA-NRP initiation time of about 7 minutes and overall duration of 87 minutes.
- Key factors for successful implementation included identifying stakeholders, maintaining communication, addressing ethical concerns, and developing care protocols for all phases of the donation process.
Objective: Re-do root replacement poses a significant technical challenge, increasing potential risk of morbidity and mortality. This multi-institution study compared outcomes in aortic root replacement stratified by chest surgery and aortic root history.
Methods: A retrospective review by the Western Aortic Collaborative was performed for three different aortic centers for patients who underwent non-emergent root replacement from 2017-2023 with exclusion of patients who underwent more than hemiarch replacement or who presented with acute or hyperacute aortic dissection.
The purpose of this study was to investigate neo-aortic curvature and diameter variation using the principal component analysis in patients who underwent a Norwood procedure for hypoplastic left heart syndrome. We further assessed whether neo-aortic curvature and diameter features are associated with clinical outcomes, single right ventricle function and flow hemodynamic patterns derived by 4D-Flow MRI. 55 patients with Fontan circulation who underwent a Norwood procedure in infancy underwent cardiac MRI as part of surveillance of their Fontan circulation.
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