Publications by authors named "T Biron-Shental"

Background: Asthma, allergic rhinitis, atopic dermatitis, and food allergy are type 2 inflammation diseases. Since the 1960s, the prevalence of those diseases has steadily increased, presumably due to the "Hygiene hypothesis" which suggests that early exposure of infants to pathogens, siblings, and environmental dust, has a protective effect against the development of allergic diseases. The COVID-19 pandemic increased environmental hygiene due to lockdowns, masks, and social distancing.

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Article Synopsis
  • The study aimed to determine if eating during labor affects outcomes by comparing food consumption to clear fluids in laboring patients.
  • 129 healthy patients were randomized into two groups: one allowed to eat and the other restricted to clear fluids, with various maternal and neonatal outcomes measured.
  • Results showed no significant differences in complications, labor progression, or outcomes between the two groups, leading to the conclusion that eating during labor is generally safe but should be approached cautiously based on individual patient risk factors.
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Purpose: To compare the immediate and late complications associated with emergent cesarean sections (CS) performed during the first and second stages of active labor.

Methods: We conducted a retrospective analysis of electronic medical records from a single academic center, including data from 577 patients who underwent emergent cesarean sections at 4 cm or more of cervical dilatation. Patients were divided into two groups: those who had CS during the first stage of labor (4-9 cm dilatation) and those who had CS at complete dilatation (10 cm).

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Article Synopsis
  • Galactin-3 is involved in crucial reproductive processes like oocyte maturation and implantation, and its expression may predict successful embryo implantation during IVF.
  • A study involving 21 women undergoing IVF measured Galactin-3 levels in blood and follicular fluid at various stages of the IVF cycle.
  • Results showed that higher Galactin-3 levels on the trigger day were associated with successful pregnancies, suggesting its role in fertility and the impact of inflammation on IVF success.
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Problem: Accelerated placental aging is linked to abnormal fetal growth, preeclampsia (PE), and preterm birth (PTB). NANOG, a transcription factor, is known for its role in cellular reprogramming, self-renewal, and clonogenic growth. Its expression is regulated by Kruppel-like factor 4 (KLF4), which functions as both a transcriptional activator and repressor.

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