Publications by authors named "T Benedek"

Myocarditis, characterized by inflammation of the myocardial tissue, presents substantial risks to cardiovascular functionality, potentially precipitating critical outcomes including heart failure and arrhythmias. This investigation primarily aims to identify the optimal cardiovascular magnetic resonance imaging (CMRI) views for distinguishing between normal and myocarditis cases, using deep learning (DL) methodologies. Analyzing CMRI data from a cohort of 269 individuals, with 231 confirmed myocarditis cases and 38 as control participants, we implemented an innovative DL framework to facilitate the automated detection of myocarditis.

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  • - The study investigates the relationship between heart health and liver disease (MASLD) in patients with type 2 diabetes (T2DM), focusing on how liver fibrosis impacts cardiac function and structure.
  • - It analyzed medical data from 267 T2DM patients with MASLD, finding that those with advanced fibrosis had thicker heart walls, larger heart sizes, and lower heart pumping efficiency compared to those without significant fibrosis.
  • - Results indicate that advanced liver fibrosis is associated with poorer cardiac function, as evidenced by lower ejection fractions and signs of diastolic dysfunction, highlighting the need for understanding these interactions in diabetes care.
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  • * Using data from 1514 patients, the model demonstrated a sensitivity of 73.2% and a high specificity of 97.8%, showing it could correctly identify calcium in coronary artery segments.
  • * The model's performance was comparable to human observers, indicating that this automated approach has strong potential for classifying coronary artery calcification efficiently.
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  • A study finds that the bacterial isolate Stenotrophomonas humi strain DIC_5 can degrade 75.1% of diclofenac in freshwater within 8 days, converting it into a metabolite called nitro-diclofenac.
  • The presence of diclofenac appears to mitigate the toxic effects of the bacterial metabolites on test organisms, including Aliivibrio fischeri and zebrafish embryos.
  • The research underscores the potential of using bacterial processes for biotransformation as an eco-friendly method to reduce harmful diclofenac levels in water.
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: Atherosclerotic disease is a major contributor to heart failure, stroke, and myocardial infarction, significantly lowering the quality of life and life expectancy and placing a significant burden on healthcare. Not all lesions deemed non-significant are benign, and conversely, not all significant lesions are causative of ischemia. Fractional flow reserve (FFR) provides a functional assessment of coronary lesions, while optical coherence tomography (OCT) offers detailed imaging of plaque morphology, aiding in therapeutic decision-making.

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