Publications by authors named "T Ben-Shushan"

Clinical practice guidelines (CPGs) and consensus-based recommendations (CBRs) require considerable effort, collaboration, and time-all within the constraints of finite resources. Professional societies, such as the International League Against Epilepsy (ILAE), must prioritize what topics and questions to address. Implementing evidence-based care remains a crucial challenge in clinical practice.

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  • A scoping review analyzed lymphoma epidemiology, treatment challenges, and patient pathways in Sub-Saharan Africa from 2011 to 2022, focusing on 84 publications, mostly from Southern and Eastern Africa.
  • Non-Hodgkin lymphoma (NHL) accounts for over 80% of cases with a significantly higher HIV comorbidity rate and younger median ages compared to Europe and the US, alongside a one-year survival rate of around 50% for NHL.
  • The study emphasizes the need to tackle diagnostic delays, misdiagnosis, and treatment abandonment through improved access to care, enhanced diagnostics, and innovative multidisciplinary approaches.
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  • * Eleven high-quality observational studies were reviewed, and results indicated early-term deliveries are linked to a 19% higher risk of type 1 diabetes, while the association with obesity was less significant.
  • * The findings underscore the importance of avoiding elective early-term deliveries whenever possible, as they may pose risks to the child's long-term health.
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Objective: Antiseizure medications (ASMs) are commonly categorized as enzyme-inducers and non-enzyme-inducers based on their propensity to enhance the metabolism of concomitantly administered drugs. This systematic review and network meta-analysis aimed to rank ASMs as cytochrome P450 3A (CYP3A)-inducers based on a comparative assessment of ASM-induced reduction in the concentrations of sensitive substrate drugs.

Methods: The protocol was registered with PROSPERO (International Prospective Register of Systematic Reviews; CRD42022335846), and the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) standards were followed.

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Background: Many health benefits of bariatric surgery are known and well-studied, but there is scarce data on the benefits of bariatric surgery on the thyroid function.

Objective: We aimed to make a meta-analysis regarding the impact of bariatric surgery on thyroid-stimulating hormone (TSH) levels, levothyroxine dose, and the status of subclinical hypothyroidism.

Setting: Systematic review and meta-analysis.

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