Publications by authors named "T Batstone"

Article Synopsis
  • Oxford ragwort (Senecio squalidus) is a unique hybrid species that provides insights into genetic changes after hybridization, due to its recent origin and specific genomic traits.
  • The study produced a comprehensive genome assembly, identifying over 30,000 protein-coding genes, with a significant portion of the genome made up of repetitive elements.
  • Key findings include evidence of varied genetic patterns among species, an unequal genetic contribution from the parent species, and the influence of genetic incompatibilities and natural selection on rapid genome stabilization in this hybrid lineage.
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Background: Diplonemid flagellates are among the most abundant and species-rich of known marine microeukaryotes, colonizing all habitats, depths, and geographic regions of the world ocean. However, little is known about their genomes, biology, and ecological role.

Results: We present the first nuclear genome sequence from a diplonemid, the type species Diplonema papillatum.

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Chloroplasts are a common feature of plant cells and aspects of their metabolism, including photosynthesis, are influenced by low-temperature conditions. Chloroplasts contain a small circular genome that encodes essential components of the photosynthetic apparatus and chloroplast transcription/translation machinery. Here, we show that in Arabidopsis, a nuclear-encoded sigma factor that controls chloroplast transcription (SIGMA FACTOR5) contributes to adaptation to low-temperature conditions.

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Article Synopsis
  • Plants develop a lipid-rich cuticle for protection against terrestrial threats, while stomata allow for gas exchange.
  • Researchers studied two genetic loci in barley linked to wax deficiency and misarranged stomata, identifying key genes responsible for these features.
  • The genes Cer-g/HvYDA1 and Cer-s/HvBRX-Solo play a crucial role in maintaining cuticular integrity, spacing of epidermal cells, and stomatal patterning, suggesting a coordinated system for adapting to environmental challenges.
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Characterisation of animal models of diabetic cardiomyopathy may help unravel new molecular targets for therapy. Long-living individuals are protected from the adverse influence of diabetes on the heart, and the transfer of a longevity-associated variant (LAV) of the human gene protects cardiac function in the mouse model. This study aimed to determine the effect of therapy on the metabolic phenotype (ultra-high-performance liquid chromatography-mass spectrometry, UHPLC-MS) and cardiac transcriptome (next-generation RNAseq) in mice.

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