Direct C-H amidation of 1,3-azoles: light-mediated, photosensitiser-free thermal.

We have developed one thermal and one light-mediated method for direct Minisci-type C-H amidation of 1,3-azoles, which are applicable to thiazoles, benzothiazoles, benzimidazoles, and for the first time, imidazoles. The new visible light-mediated approach can be rendered photosensitiser/photocatalyst-free and likely proceeds an electron donor-acceptor (EDA) complex, the first direct Minisci-type amidation to do so.

Evidence-based recommendations for musculoskeletal kinematic 4D-CT studies using wide area-detector scanners: a phantom study with cadaveric correlation.

Propose: To establish evidence-based recommendations for musculoskeletal kinematic 4D-CT on wide area-detector CT.

Materials And Methods: In order to assess factors influencing image quality in kinematic CT studies, a phantom consisting of a polymethylmethacrylate rotating disk with round wells of different sizes was imaged with various acquisition protocols. Cadaveric acquisitions were performed on the ankle joint during motion in two different axes and at different speeds to allow validation of phantom data.

[Dose reduction at CT of the lumbar spine using a 320-detector row scanner: initial results].

Purpose: To compare radiation dose and image quality for CT of the lumbar spine between helical CT and wide volume mode scanning with a 320-detector row CT.

Patients And Methods: Monocenter prospective study on 20 consecutive patients divided into two groups. All 20 patients underwent lumbar spine CT on the 320-detector row scanner (Aquilion One, Toshiba).

[Bone marrow edema: definition, diagnostic value and prognostic value].

Bone marrow edema is easily identified on MRI. The terminology suggests that the water content of bone marrow is increased when it is T1W hypointense and T2W hyperintense. It is a misnomer since, histologically, the abnormality does not correspond to marrow edema.