Publications by authors named "T Barna"
Article Synopsis
- Aquaporins (AQPs), particularly AQP5, play a crucial role in pregnancy-related functions such as implantation and uterine contractions, though the exact mechanisms are still unclear.
- A study on late-pregnant rats showed that reducing AQP5 levels led to shorter gestational periods and increased uterine contractions, particularly after treatment with AQP5 siRNA.
- The research indicates that AQP5 interacts with the adrenergic system, which can influence uterine contractions; these insights may pave the way for new treatments to manage preterm labor.
Determining the female animal cycle is crucial in preclinical studies and animal husbandry. Changes in hormone levels during the cycle affect physiological responses, including altered contractility of the visceral smooth muscle. The study aimed to identify estrus and anestrus using smooth muscle electromyographic (SMEMG) measurements, in vivo fluorescent imaging (IVIS) and in vitro organ contractility of the uterus and cecum.
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- The detection of gravitational-wave signal GW170817 and its associated phenomena (kilonova and gamma-ray burst) marked a significant advance in astrophysics, indicating the need for strong theoretical models to interpret these diverse signals.
- The NMMA framework was developed to integrate nuclear-physics data and observational evidence, helping to analyze the behaviors of dense matter in neutron stars.
- This paper presents an extension of the NMMA code to simultaneously analyze the signals from GW170817, the kilonova, and the gamma-ray burst, allowing for the estimation of a neutron star's radius.
Aims: Our aims were to investigate the uterus relaxant effect of sildenafil alone and co-administered with β-mimetic terbutaline in an isolated organ bath and to perform in vivo smooth muscle electromyographic studies in pregnant rats. The modifications in uterine cAMP/cGMP levels were also detected.
Main Methods: Contractions of non-pregnant and 5/15/18/20/22-day pregnant uterine rings were measured in an isolated organ bath system in the presence of sildenafil alone or with terbutaline.