Publications by authors named "T Barjat"

Article Synopsis
  • A scientific expert committee reanalyzed suspected clusters of transverse upper limb reduction defects (TULRD) in France from 2019-2021, addressing public health concerns despite no initial risk exposure findings.
  • Methods included reviewing medical records, conducting spatiotemporal analyses for statistical significance, and examining environmental exposures through questionnaires and surveys.
  • Results showed no significant clusters in one area, a small cluster in another without identifiable risk factors, and only two cases in a third area, emphasizing the need for a standardized approach in managing similar health concerns.
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Introduction: Objective Structured Clinical Examinations (OSCEs) assess professional performance in a simulated environment. Following their integration into the reform of the 2nd cycle of medical studies (R2C), this pedagogical modality was implemented in France. This study investigates the variability of students' OSCE scores, as well as their inter-rater reproducibility.

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Article Synopsis
  • Pregnant women are at higher risk for serious complications from seasonal influenza and Covid-19, making vaccination critical during pregnancy for both the mother and her newborn.
  • A survey of 310 pregnant women showed varying levels of intention to get vaccinated against influenza (43.9%), Covid-19 (36.8%), pertussis (36.1%), and RSV (39.4%).
  • Factors boosting vaccine acceptance included trust in vaccines, recommendations from healthcare providers, knowledge about diseases, and past flu vaccinations.
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  • Oxytocin can shorten labor but may cause complications, leading researchers to investigate if stopping the drug during labor affects neonatal outcomes.
  • The STOPOXY trial, conducted in 21 French maternity units, randomly assigned participants to either stop or continue oxytocin infusion after reaching 6 cm dilation, measuring neonatal morbidity based on specific health indicators at birth.
  • The study included 2,170 eligible participants, finding no significant difference in neonatal morbidity between the two groups, suggesting that discontinuing oxytocin may not increase risks for newborns.
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Article Synopsis
  • - The cellular prion protein (PrP) is a glycoprotein found on cell surfaces, primarily in the brain and peripheral tissues, linked to various functions including signaling, copper homeostasis, and cell adhesion.
  • - PrP is implicated in neurodegenerative diseases and has been found to be expressed in multiple types of cancers, where it aids in tumor growth, cellular invasion, and resistance to chemotherapy.
  • - The review highlights the varied expression of PrP in different cancers and suggests its potential as a therapeutic target for cancer treatment.
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