Publications by authors named "T Barber"
Background: SARS-CoV-2 antibody levels have been proposed as a correlate of protection (CoP) from infection. Yet, large-scale prospective studies of cost-effective scalable antibody measures as predictors of infection under real-world conditions are limited. We examined whether antibody levels measured using high-throughput variant-specific SARS-CoV-2 anti-spike immunoglobulin G (IgG) and ACE2-neutralization assays correlate with cell-based neutralizing antibody (NAb) measurements, and whether they can serve as a reasonable CoP from SARS-CoV-2 infection.
View Article and Find Full Text PDFTire and road wear particles (TRWP) are generated at the frictional interface between tires and the road surface. This mixture of tire tread and road pavement materials can migrate from roads into nearby water bodies during precipitation events. The absence of mass-based measurements in marine environments introduces uncertainty in environmental risk assessments and fate and transport models.
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- Heart failure is prevalent among hemodialysis patients, and high flow arteriovenous fistulas (AVFs) may be a risk factor; this study aims to create a predictive model to identify patients at risk of developing high flow AVFs.
- Using data from 366 patients, the study compared various machine learning models to predict high flow AVF development, finding that the bootstrap forest model was the most effective.
- Results showed that while 31.4% of patients had high flow AVFs, and 24.9% developed heart failure after AVF creation, no direct correlation was found between AVF flow and the onset of heart failure or death post-creation.
Article Synopsis
- - Arteriovenous fistula (AVF) is the ideal vascular access for patients undergoing hemodialysis, created by surgically connecting an artery and vein, but research indicates that many do not function beyond a year.
- - This study utilized fluid-structure interaction (FSI) modeling to analyze non-Newtonian blood flow in a specific type of AVF over a 15-week and 1.5-year period, assessing both hemodynamic changes and wall alterations through ultrasound.
- - Key findings included the presence of counter-rotating vortices affecting pressure, different patterns of blood flow characteristics over time, minimal low-wall shear stress in healthy AVFs, and shifts in areas of maximum wall deformation as time