Publications by authors named "T Badger"
Background: The purpose of this study was to test dyadic interdependence in psychological distress (anxiety and depressive symptoms) and explore moderators of interdependence among cancer survivors in treatment and their informal caregivers.
Methods: Cancer survivors and their caregivers completed measures of anxiety and depressive symptoms, social support, social isolation, and burden of other symptoms, at three points in time over the course of 17 weeks.
Results: In 315 dyads, depressive symptoms and anxiety were transmitted from caregivers to survivors.
Article Synopsis
- * A two-part study was conducted to create and evaluate a website that hosts the TOGETHER intervention, with a focus on enhancing usability and ensuring it meets the specific needs of young adults aged 15-39 diagnosed with cancer.
- * Usability testing indicated that the website was user-friendly, while the feasibility trial showed promising recruitment, retention, and attendance rates, confirming its potential effectiveness among participants.
Purpose: Three sequences of telephone symptom management interventions were tested on use of unscheduled health services among cancer survivors with depressive or anxiety symptoms during treatment (N = 334) and their informal caregivers (N = 333).
Methods: The three 12-week intervention sequences were as follows: (1) Symptom Management and Survivorship Handbook (SMSH), (2) a combined 8-week SMSH + Telephone Interpersonal Counseling (TIPC) followed by SMSH for 4 weeks, and (3) SMSH for 4 weeks followed by a combined SMSH + TIPC if no response to SMSH alone. Survivor-caregiver dyads were first randomized to SMSH or a combined SMSH + TIPC.
Objective: To compare in-hospital and neurodevelopmental (ND) outcomes between very preterm infants conceived spontaneously and those conceived utilizing in vitro fertilization (IVF).
Study Design: A 10-year retrospective study of a large regional, mixed urban and rural population was conducted. IVF conceived infants born <32 0/7 weeks gestational age (GA) were matched 1:2 to control patients who did not undergo any documented assisted reproductive technology (ART) based on GA, birth weight and gender.
Article Synopsis
- - Classic galactosemia (CG) is linked to mutations in the GALT gene and leads to early ovarian insufficiency (POI) in 80% of women due to a decrease in ovarian reserve, though the underlying mechanisms are still unclear.
- - This study utilized advanced techniques like single-nucleus RNA sequencing to analyze ovary biopsies from prepubertal girls with CG, revealing seven key cell types and identifying disruptions in gene expression related to stress responses and cell survival.
- - The research highlighted significant changes in signaling pathways associated with ovarian function, indicating increased cellular stress and damage in primordial follicles, which could explain accelerated follicular loss in CG patients.