[The Dual Nature of the Electrical Signals of the Brain (Electrical and Electrochemical) Which Were Recorded With the Help Polarizable Electrodes From Inert Metals].

In the modern neurophysiology opinion was confirmed that the electrical signals of the brain in the frequency band from DC to electroencephalogram recorded with metallic conductors of inert metal implanted in the brain are formed solely by changes in the electric field of the brain. This paper presents a review of the literature and our own data, according to which the formation of these signals involves two factors. One factor is a change in the charge of the electric double layer electrode having a capacitor property and change the value of its charge with changes in the electric field volume conductor--the brain.

[Effect of disulfiram on energy metabolism (redox potential shift) coupled to paradoxical sleep episodes in rat cerebral cortex].

Disulfiram (DS) is widely used to treat patients with chronic alcoholism. DS treatment multiplies PS episodes. In this work, DS effect on the number of PS episodes and on the energy metabolism changes in the cerebral cortex (coupled to PS episodes) was investigated for the first time in rats.

[Weak irregular periodical winces of rats in slow wave sleep (SWS) coupled to the cerebral cortex activation and local falls in the cortex redox potential (E)].

The current study has been fulfilled to advance our pioneer studies of the brain energy metabolism (EM) in animals [Shvets-Teneta-Gurii T. B., 1979: Shvets-Teneta-Gurii T.

Changes in the redox potential of the rabbit cerebral cortex accompanying episodes of ECoG arousal during slow-wave sleep.

The redox potential (E) is a useful measure of the intensity and quality of shifts in energy metabolism. Brain E depends on the ratio of the rates of processes occurred in two compartments of energy metabolism - the glycolysis compartment, in which glucose is split without oxygen, and the oxidative metabolism compartment. The present report describes recording of local changes in E using platinum electrodes implanted into several points in the cortex.

Local changes in the redox potential in the rabbit cerebral cortex accompanying the acquisition of a conditioned defensive reflex.

The oxidative-reductive (redox) potential (E) of brain tissue depends on the ratio of the speeds of processes occurring in the glycolysis (the evolutionarily ancient energy compartment operating without oxygen) and oxidative metabolism (evolutionarily younger and energetically more efficient) compartments. E in the cortex was recorded using implanted platinum electrodes. A conditioned defensive reflex (CDR) was developed by combination of a light and electrocutaneous stimulation (ECS) of the ear.