[Prediction of orthopedic sequels of operated tuberculous ostitis in children].

Thirteen of 84 children with tuberculous ostitis of the proximal tibial portion were repeatedly operated on 1.5 to 12 years after radical reconstructive surgery due to developed orthopedic sequels. Deformities of the tibia were found to develop in the earliest period and tibial shortening formed significantly later.

[Changed life quality in patients with tuberculosis and other diseases of large joints after surgical treatment].

The quality of life was studied in 88 patients who had been operated on for tuberculosis and other diseases of the hip and knee joints. Reconstructive surgery was ascertained to considerably relieve painful sensations, to permit the better capacities of patients' movements. Multifactorial analysis of life quality in patients demonstrated the obvious advantages of reparative mobilizing operations on the joints over arthrodesing ones.

[Characterization of destructive pulmonary tuberculosis (by the results of a clinicomathematical analysis)].

The results of examination of 56 patients with destructive pulmonary tuberculosis, which involved the study of biochemical parameters characterizing different stages of an inflammatory process, as well as clinical and X-ray findings were analyzed, by applying various multivariate statistical methods. This approach was shown to be promising for estimating the severity of the process and for specifying the stage of development of an inflammatory process in some patients.

[The activity of alpha2-macroglobulin and its forms in patients with destructive pulmonary tuberculosis].

A hundred and three patients with destructive pulmonary tuberculosis were examined. These patients had heterodirectional changes in the serum levels of alpha2-macroglobulin (MG) and its forms. The lowering of the level of the F-form of the inhibitor outstripped the decrease in the activity of total alpha2-MG and it was detectable in the lobar processes with moderate symptoms of intoxication and with the inoculation of adjacent segments.

[Prediction of the effectiveness of preoperative preparation of patients with fibro-cavernous pulmonary tuberculosis].

Sixty-three patients with fibrocavernous pulmonary tuberculosis were examined before and 1 month after preoperative therapy with antituberculosis agents. The time course of changes in the clinical and X-ray characteristics of the severity of the disease were compared with the alterations of different biochemical indices, including acute-phase proteins, proteolysis inhibitors, intoxication severity. It was demonstrated that improvement of clinical and X-ray characteristics of the severity of a process after preoperative preparation could be predicted with an accuracy of 83% from the baseline serum concentrations of albumin and ceruloplasmin.