Publications by authors named "T B K Sinha"

Negative attitudes toward persons with disabilities (PWDs) can lead to stigmatization and exclusion, underscoring the need for effective tools to measure and address such attitudes in educational settings. This study compares the psychometric properties of two scales used to assess attitudes toward PWDs among health science learners: the Multidimensional Attitudes Scale Toward Persons with Disabilities (MAS) and the Attitudes and Perspectives Toward Persons with Disabilities Scale (APPD). This research examines the internal consistency, factor stability, factor replicability, and convergent validity of these scales across different measurement occasions using data from second-year Medical (n = 102) and Doctor of Physical Therapy (n = 39) students.

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Cellulase production for hydrolyzing plant cell walls is energy-intensive in filamentous fungi during nutrient scarcity. AMP-activated protein kinase (AMPK), encoded by snf1, is known to be the nutrient and energy sensor in eukaryotes. Previous studies on AMPK identified its role in alternate carbon utilization in pathogenic fungi.

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High-throughput sequencing technologies and innovative bioinformatics tools discovered that most of the genome is transcribed into RNA. However, only a fraction of the RNAs in cell translates into proteins, while the majority of them are categorized as noncoding RNAs (ncRNAs). The ncRNAs with more than 200 nt without protein-coding ability are termed long noncoding RNAs (lncRNAs).

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Our previous study explored the bacterial endophytic diversity in a certain quantity of mustard seeds using culture dependent method by development of new isolation strategies. No bacterial colony was initially observed in supernatant obtained after centrifugation of mustard seed suspension. This was later overcome by usage of surfactant whereas pellet part showed presence of bacterial colonies on media.

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Article Synopsis
  • The study aimed to assess the visual and anatomical outcomes in diabetic macular edema (DME) patients who switched from intravitreal Aflibercept (IVI AFL) to biosimilar Ranibizumab (B-RBZ) due to financial reasons rather than efficacy issues.
  • A total of 57 DME patients were observed, showing substantial improvement in visual acuity during treatment with Aflibercept and a slight decline after switching to Ranibizumab, but overall vision remained better than the initial baseline.
  • The transition maintained anatomical stability in terms of central macular thickness and reduced subretinal and intra retinal fluid levels, indicating that biosimilar Ranibizumab is an effective and cost-efficient therapeutic option
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