Publications by authors named "T B Causey"

Shprintzen-Goldberg craniosynostosis syndrome (SGS) is a rare autosomal dominant condition that was first documented in literature in 1982. The disorder is caused by pathogenic variants in the proto-oncogene gene, a known suppressor of TGF- activity, located on chromosome 1p36. There is considerable phenotypic overlap with Marfan and Loeys-Dietz syndromes.

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The yeast has been a successful host for the production of heterologous proteins for over 30 years. Currently, the galactose-/lactose-inducible and glucose-repressible promoter (P ) is the most widely used promoter to drive recombinant protein expression in However, P is not fully repressed in the presence of glucose and significant protein expression still occurs. Thus, P is not suitable in processes where tight regulation of heterologous gene expression is required.

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