Publications by authors named "T B Averina"

Article Synopsis
  • Cardiopulmonary bypass practices in pediatric patients are evolving, driven by new technologies and techniques, with a focus on gathering updated international data since 2016.
  • A recent survey in July 2021 garnered responses from 153 of 284 pediatric cardiac surgery centers worldwide, reflecting a diverse range of practices in equipment and techniques.
  • Key findings include widespread use of roller head pumps (93%), hollow fiber oxygenators (86%), and selective antegrade cerebral perfusion (92%), indicating significant trends and variations in pediatric perfusion practices globally.
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New cardiopulmonary bypass device techniques emerge and are reported in the scientific literature. The extent to which they are actually adopted into clinical practice is not well known. Since 1989, we have periodically surveyed pediatric cardiac centers to ascertain practice patterns.

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The paper presents the results of studying the perfusion and postoperative periods in 24 neonates and babies weighing less than 5 kg who have undergone radical and hemodynamic correction of transposition of the great arteries under extracorporeal circulation. According to whether the phosphorylcholine coating of an extracorporeal circuit was available, the patients were allocated into 2 groups: (1) Phisio and (2) coating-free. Based on the time course of changes in the count of white blood cells and platelets and in the activity of aspartate aminotransferase, neutrophil elastase, and antitrypsin, in the levels of tumor necrosis factor-alpha, IL-8, and IL-10, in postperfusion hemohydrobalance, and in the indicators of the clinical course in the postoperative period, the authors have concluded that a reduction in infectious complications (from 75 to 11%) and simplification of the pattern of noninfectious pathology in the Phisio group are associated with a more balanced systemic inflammatory response and less tissue damage.

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