Obesity as a modifying factor of periodontal therapy outcomes: local and systemic adipocytokines and oxidative stress markers.

Objectives: Adipocytokines and oxidative stress (OS) are involved in the pathogenesis of both obesity and periodontitis. The aim of this study was to evaluate periodontal therapy outcomes in terms of serum and gingival crevicular fluid (GCF) levels of adipocytokines and OS markers in obese patients with periodontitis, in order to have an insight into the association between obesity and periodontitis.

Materials And Methods: A total of 39 patients (20 obese, 19 non-obese) with periodontitis were included in this study.

Methodological evaluation of gingival crevicular fluid volume and neutrophil elastase levels: sequential sampling, length of sampling time and two different sampling methods.

The mechanisms underlying the formation and composition of gingival crevicular fluid (GCF) and its flow into and from periodontal pockets are not understood very well. The aim of this study was to evaluate the length of sampling time and sequential sampling of GCF neutrophil elastase (NE) enzyme levels by using intracrevicular and orifice methods. Twenty adults (mean age of 41.

Evaluation of long-term effects of diode laser application in periodontal treatment of poorly controlled type 2 diabetic patients with chronic periodontitis.

Purpose: This study aimed to investigate the effects of diode laser (DL) in addition to non-surgical periodontal treatment on periodontal parameters, systemic inflammatory response and serum haemoglobin A (HbA ) level in patients with poorly controlled type 2 diabetes mellitus (T2DM) and chronic periodontitis.

Methods: Thirty-seven patients with poorly controlled T2DM and chronic periodontitis completed this study. The patients were divided into two groups.

Effects of a cyclic NSAID regimen on levels of gingival crevicular fluid prostaglandin Eand Interleukin-1β: A 6-month randomized controlled clinical trial.

Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for inflammation control and pain relief. However, while the adjunct use of NSAIDs is avoided for periodontal therapy because of related side effects, cyclic administration of NSAIDs may reduce or eliminate these effects. We evaluated the effect of a cyclic diclofenac potassium (DP) regimen on clinical parameters and levels of prostaglandin E (PGE) and interleukin-1β (IL-1β) in the gingival crevicular fluid (GCF) of individuals with periodontitis.

Apoptosis: an underlying factor for accelerated periodontal disease associated with diabetes in rats.

Objectives: Diabetes mellitus (DM) is well-established risk factor for periodontal disease. DM can also lead to changes in the number of apoptotic cells in periodontal tissues. The goal of this study was to evaluate apoptosis, depending on DM, in healthy and diseased periodontal soft tissues.