Publications by authors named "T Aspelund"
Importance: Comprehensive data on the prevalence of various life stressors and their role in posttraumatic stress disorder (PTSD) among women are lacking.
Objective: To determine the prevalence of a broad range of life stressors and their association with PTSD in a large nationally representative cohort of women.
Design, Setting, And Participants: This cross-sectional analysis used data from the population-based Stress-And-Gene-Analysis, which invited women in Iceland to complete an online survey from March 1, 2018, to July 1, 2019.
Article Synopsis
- - Individuals with mental illness are at a higher risk for severe COVID-19 outcomes, but studies on their vaccination uptake have shown mixed results.
- - This research analyzed data from multiple cohort studies and Swedish registers to explore the relationship between mental illness and COVID-19 vaccination rates.
- - Findings revealed that while overall vaccine uptake was high in both groups, there was a slight decrease in vaccination rates among unmedicated individuals with mental illness, indicating a need for further investigation into this subgroup.
Article Synopsis
- The study analyzed serum proteins in 5,127 older Icelandic adults to gain insights into the molecular processes of late-onset Alzheimer's disease (LOAD) over nearly 13 years.
- Researchers identified 303 proteins linked to incident LOAD, with over 40% showing independent associations from the APOE-ε4 gene variant, indicating involvement in neuronal functions.
- Four proteins were found to be downregulated by APOE-ε4 but upregulated in LOAD, suggesting they may reflect a biological response to the onset of the disease, highlighting dysregulated processes early in LOAD development.
Male-female spatio-temporal differences of age-related bone changes show faster bone deterioration in older women at femoral regions associated with incident hip fracture.
J Bone Miner Res
September 2024
A better understanding of how age-related bone loss affects the fracture-prone regions of the proximal femur could lead to more informed fracture-prevention strategies. Therefore, the aim of this work was to assess the spatio-temporal distribution of bone deterioration in older men and women with aging. A subset of 305 men (74.
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