Genetic Insights Into Recurrent Granular Cell Tumours in an Adolescent: The Role of Cytology and Next-Generation Sequencing in the Diagnosis of RASopathies.

Rasopathies are a group of genetic disorders that involve abnormal Ras/mitogen-activated protein kinase (RAS/MAPK) pathway signalling, which has a mechanistic approach to defining genetic syndromes and makes them unique. Noonan syndrome, a form of RASopathy, occurs with advanced paternal age and has an autosomal dominant inheritance. It has been suggested that aberrant RAS/MAPK pathway cell signalling may cause multiple benign granular cell tumours.

Optimized Production and Characterization of Auxin by Bacillus amyloliquefaciens (TSP11) for Plant Growth Promotion.

This study was aimed at isolating and recognizing the plant growth promoting rhizobacteria that secretes indole-3-acetic acid/auxin hormones. Among the 82 pure cultured bacterial morphotypes, the strain TSP11 showed high auxin production utilizing rice husk as a cheap substitute in the production medium. The minimal medium supplemented with 0.

Purification and characterization of detergent stable alkaline lipase from TKW3 isolated from Tso Kar brackish water lake.

Unlabelled: Extensive and escalating research has been directed towards halozymes derived from halophiles thriving in extreme hypersaline environments, owing to their myriad industrial applications. These extremophiles have evolved various physiological and metabolic adaptations to endure such extremes, enhancing their industrial potential. Being a potential source of lipases, halophiles of extreme niches have emerged as a emerging research area.

Biocontrol efficacy of native (Hypocreales: Clavicipitaceae) isolates against (F) (Lepidoptera: Noctuidae) and in silico effect of the secondary metabolites against the virulent proteins of the insect.

This study explores the insecticidal potential of secondary metabolites derived from against through an integrative approach involving genomics, metabolomics, and bioinformatics. Four native isolates of were identified and characterized for their insecticidal efficacy. Among these, the SlMr-DOR isolate exhibited the highest effectiveness, achieving a remarkable 90.