Publications by authors named "T Asami"
The smoke-derived butenolides, karrikins (KARs), regulate many aspects of plant growth and development. However, KARs and a plant hormone, strigolactones (SLs), have high resemblance in signal perception and transduction, making it hard to delineate KARs response due to the shortage of chemical-genetic tools. Here, we identify a triazole urea KK181N1 as an inhibitor of the KARs receptor KAI2.
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- Enhancing crop productivity is crucial for food security, and biostimulants like zaxinone and its mimics show promise in boosting plant growth and yield.
- Their application was studied to see how they affect soil and rice root microbiota, focusing on bacterial and fungal communities at different growth stages.
- Results indicate that these treatments initially reduced beneficial microbes in the roots but allowed for a recovery in microbial diversity later, highlighting their potential as eco-friendly solutions for agriculture.
Brassinosteroids (BRs) are plant steroid hormones that regulate plant development and environmental responses. BIL1/BZR1, a master transcription factor that regulates approximately 3000 genes in the BR signaling pathway, is transported to the nucleus from the cytosol in response to BR signaling; however, the molecular mechanism underlying this process is unknown. Here, we identify a novel BR signaling factor, BIL7, that enhances plant growth and positively regulates the nuclear accumulation of BIL1/BZR1 in Arabidopsis thaliana.
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- Researchers developed a new PET tracer, [C]K-2, that allows for the visualization and measurement of AMPAR density in the brains of living human patients, which is important for understanding neurotransmission in psychiatric disorders.
- The study involved 149 patients with various psychiatric disorders (like schizophrenia and bipolar disorder) and 70 healthy individuals, revealing correlations between AMPAR density and symptom severity.
- The findings highlight unique patterns of AMPAR distribution across different psychiatric disorders, suggesting potential new approaches for diagnosing and treating these conditions based on biological mechanisms.
Biological aging analysis based on DNA methylation status for social anxiety disorder.
Neuropsychopharmacol Rep
December 2024
Article Synopsis
- Social Anxiety Disorder (SAD) is linked to a higher risk of aging-related diseases, and researchers used epigenetic analysis to explore this connection.
- The study analyzed DNA methylation data from 66 SAD patients and 77 controls, focusing on age acceleration and predictive values of specific proteins.
- Findings showed no significant age acceleration between groups, but indicated that leptin levels were significantly lower in SAD patients, suggesting its potential role in the disorder's development.