Publications by authors named "T Arora"
There is somatotopic organization of body in motor and sensory cortex of brain. Distal parts of a limb have a much larger area of presentation as compared to proximal parts. So, isolated distal hand muscle weakness as a manifestation of stroke is not so uncommon, but isolated shoulder muscle weakness as a manifestation of stroke is very rare.
View Article and Find Full Text PDFContext: Excessive eating and intake of a Western diet negatively affect the intestinal immune system, resulting in compromised glucose homeostasis and lower gut bacterial diversity. The G protein-coupled receptor GPR183 regulates immune cell migration and intestinal immune response and has been associated with tuberculosis, type 1 diabetes, and inflammatory bowel diseases.
Objective: We hypothesized that with these implications, GPR183 has an important immunometabolic role and investigated this using a global Gpr183 knockout mouse model.
Background: Both night-eating syndrome and binge-eating disorder are characterized by episodes of excessive food consumption, significant distress, and functional impairment related to maladaptive eating behaviors. Both types of eating disorders are associated with poorer sleep quality. Cognitive behavioral therapy has demonstrated good outcomes for binge-eating disorder; however, it is unknown if it is effective for night-eating syndrome and comorbid insomnia.
View Article and Find Full Text PDFBackground & Aim: Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder that affects women throughout their reproductive age and characterised via polycystic ovaries, hyperandrogenism, and irregular menstruation. There is rising evidence that the pathophysiology of PCOS is significantly affected via the gut microbiota and its metabolic products.
Methods: This narrative review synthesizes current literature exploring the relationship between gut microbiota and PCOS.
Article Synopsis
- This study aimed to estimate the nationwide prevalence of polycystic ovary syndrome (PCOS) in India and analyze the associated comorbidities among women aged 18 to 40 years.
- The research involved a large cross-sectional survey of 9,993 women, identifying varying prevalence rates of PCOS based on different diagnostic criteria: 7.2% (NIH), 19.6% (Rotterdam), and 13.6% (AE-PCOS).
- Results indicated younger average ages in women diagnosed with PCOS and highlighted the need for better-designed studies to understand the full spectrum of PCOS phenotypes and health implications in Indian women.