Publications by authors named "T Araya-Contreras"
Article Synopsis
- The study aimed to assess the prevalence of uropathogens in dogs and cats showing signs of urinary tract infections and analyze their antimicrobial resistance patterns.
- Over the research period from 2015 to 2019 in Santiago, Chile, a significant number of urine samples from both dogs (37.7%) and cats (26.1%) tested positive for bacterial growth, with Escherichia coli being the most frequently isolated pathogen.
- High levels of antibiotic resistance were found among the bacteria, particularly against common medications like amoxicillin and fluoroquinolone, which poses public health concerns regarding managing infections in pets.
In this study, we report a facile transformation starting from 5α-hydroxyergosta-7,22-dien-3,6-dione to afford two novel compounds: 6-methoxyergosta-4,6,8(14),22-tetraen-3-one and 6-ethoxyergosta-4,6,8(14),22-tetraen-3-one ( using alcoholic acid catalysis. Their structures were elucidated using NMR experiments, FT-IR, MS and X-ray analysis. These compounds were evaluated for antibacterial activity using the disk and broth diffusion test.
View Article and Find Full Text PDFNosocomial infections caused by bacteria are one of the main public health problems. Moreover, the resistance to antibiotics by these bacteria makes it necessary to find new treatments to fight them. .
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