Publications by authors named "T Arab"

Article Synopsis
  • Extracellular vesicles (EVs) are tiny particles released by all cells and have a significant role in communication, shuttling substances, and modulating the immune system, especially relevant in multiple sclerosis (MS) research.
  • The study focused on mouse models of MS to analyze the changes in EVs from the spinal cord at different stages of the disease, revealing shifts in proteins related to inflammation and synaptic function.
  • The findings indicate that EVs reflect critical disease mechanisms in the central nervous system (CNS) and suggest potential biomarkers for MS, with similarities between changes in EVs in experimental models and those seen in human MS patients.
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Background: no-reflow can complicate up to 25% of pPCI and is associated with significant morbidity and mortality. We aimed to compare the outcomes of intracoronary epinephrine and verapamil with intracoronary adenosine in the treatment of no-reflow after primary percutaneous coronary intervention (pPCI).

Methods: 108 STEMI patients had no-reflow during pPCI were assigned into four groups.

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Preeclampsia (PE) is a disease in pregnancy that is characterized by new-onset hypertension end-organ dysfunction, often occurring after 20 weeks of gestation. Risk factors include a prior history of PE, diabetes, kidney disease, obesity, and high maternal age at pregnancy. Current treatment and management guidelines focus on the management of high blood pressure and any potential complications.

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Extracellular vesicles (EVs) are released from different cell types in the central nervous system (CNS) and play roles in regulating physiological and pathological functions. Although brain-derived EVs (bdEVs) have been successfully collected from brain tissue, there is not yet a "bdEV Atlas" of EVs from different brain regions. To address this gap, we separated EVs from eight anatomical brain regions of a single individual and subsequently characterized them by count, size, morphology, and protein and RNA content.

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Background This study was conducted to explore the association between postpartum depression (PPD) and mode of delivery in pregnant women. Methods This cross-sectional study was conducted in the western region of Saudi Arabia, among 173 women from the general population who met the inclusion criteria and participated in the study from April to September 2022. The Edinburgh Postnatal Depression Scale (EPDS) was used to assess PPD.

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