Phosphorylation regulates mycobacterial proteasome.

Mycobacterium tuberculosis possesses a proteasome system that is required for the microbe to resist elimination by the host immune system. Despite the importance of the proteasome in the pathogenesis of tuberculosis, the molecular mechanisms by which proteasome activity is controlled remain largely unknown. Here, we demonstrate that the α-subunit (PrcA) of the M.

Characterization of a chromosomal toxin-antitoxin, Rv1102c-Rv1103c system in Mycobacterium tuberculosis.

Toxin-antitoxin systems, ubiquitous in prokaryotic genomes, have been proposed to play an important role in several stress responses. While Mycobacterium tuberculosis contains more than 80 putative TA loci, the roles they play in this pathogen are yet to be studied. Here, we characterize a chromosomal Rv1102c-Rv1103c TA system in M.

Humoral classification of diseases in Siddha system of medicine.

In siddha system of medicine the total number of diseases are said to be 4448, but the subclassification methodology and enumeration differ from one source to another. However, classification of the majority of these diesases is either based on clinical symptoms or vitiation of humor. Futher they have been sub-classified on the basis of the predominent symptoms, affected organs and aetiological factors.

Preparation of "777 oil" used for psoriasis in siddha medicine by modified method.

"777 oil" a coded drug of Siddha system of medicine was prepared and analyzed in the paper. The drug showed 3.62, 13.

Process and product standardisation of "77 oil" used for psoriasis in siddha medicine.

"777 oil" is a code drug of the Siddha system of medicine used in the treatment of Psoriasis. The drug is derived from the leaves Wrightia tinctoria by insolation, with coconut oil as base. The present study is aimed at comparing the drug prepared by insolation with that prepared in darkness.