Background Functional claim-associated foods contain raw materials that contribute to enhancing health in Japan. However, certain foods with functional claims fail to meet the disintegration test (DT) criteria of the Japanese Pharmacopoeia (JP). Objective This study assessed the quality of tablet-type, functional claim-associated foods containing Salacia-derived salacinol, using DT and weight variation (WV) tests.
View Article and Find Full Text PDFIn this study, we experimentally demonstrated that the nonlinear optical coefficient of the original Si can be enhanced by incorporating a metamaterial structure into an existing silicon waveguide. The two-photon absorption coefficient enhanced by the metamaterial structure was 424 cm/GW, which is 1.2 × 10 times higher than that of Si.
View Article and Find Full Text PDFInt J Clin Pharmacol Ther
December 2024
Objective: Tazobactam/piperacillin is a first-line treatment option for hospital-acquired pneumonia; however, drug-induced liver injury (DILI) is relatively frequently observed with tazobactam/piperacillin in clinical practice. This study aimed to verify the usefulness of available patient data for predicting DILI prior to tazobactam/piperacillin administration.
Materials And Methods: Tazobactam/piperacillin-treated patients were retrospectively selected and divided into patients with and without DILI.