Publications by authors named "T Aloe"

Background: Persistent dyspnea is frequent in post-COVID patients, even in the absence of pulmonary embolism (PE). In this scenario, the role of lung perfusion scintigraphy is unclear. The present study correlated scintigraphy-based semiquantitative perfusion parameters with chest high-resolution computed tomography (hrCT) volumetric indexes and clinical data in post-COVID patients with persistent dyspnea.

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Article Synopsis
  • This study examines the long-term effects of COVID-19 (Long COVID) in patients infected with different strains of the SARS-CoV-2 virus over two years.
  • It involved analyzing demographic and clinical characteristics of 308 Italian patients, focusing on symptoms like fatigue and dyspnoea, as well as impacts on quality of life (QoL) during different waves of infection.
  • The findings indicate that while overall L-COVID symptoms were consistent across strains, the experience of pain was notably higher during the initial wave, and some QoL dimensions improved over six months, though others, like anxiety-depression, did not show significant change.
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Introduction: Recent evidence suggests that oxidative stress and endothelial dysfunction play critical roles in the pathophysiology of COVID-19 and Long-COVID. We hypothesized that a supplementation combining L-Arginine (to improve endothelial function) and Vitamin C (to reduce oxidation) could have favorable effects on Long-COVID symptoms.

Methods: We designed a survey (LINCOLN: L-Arginine and Vitamin C improves Long-COVID), assessing several symptoms that have been associated with Long-COVID to be administered nationwide to COVID-19 survivors; the survey also included effort perception, measured using the Borg scale.

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Article Synopsis
  • * Researchers collected data from 109 patients and utilized logistic regression and clustering analysis to assess demographic information, COVID severity, and related symptoms, identifying two distinct types of neurological long-COVID.
  • * Findings revealed that long-COVID type 1 involved memory and psychological issues, while type 2 was associated with peripheral nervous system symptoms, highlighting the relationship between the severity of initial COVID-19 infection and neurological complications experienced afterward.
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