Microspheres based on galactomannan and Spondias purpurea L. extract to increase antifungal and antibiofilm efficacy against Candida spp.

The ongoing problem of an increasing resistance of Candida spp. to available antifungals, has made it necessary the search for new therapeutic alternatives. The aim of this work was to develop a microsphere based on Caesalpinia ferrea galactomannan and Spondias purpurea L.

Let-7b, miR-29b, and miR-125b as Potential Biomarkers for Differentiating Canine Mammary Carcinoma Histological Types.

Epigenetics is the study of changes in organisms that result from modifications in gene expression rather than alterations in the genetic code itself [...

The effects of teleconnections on water and carbon fluxes in the two South America's largest biomes.

Ecosystem services provided by terrestrial biomes, such as moisture recycling and carbon assimilation, are crucial components of the water, energy, and biogeochemical cycles. These biophysical processes are influenced by climate variability driven by distant ocean-atmosphere interactions, commonly referred to as teleconnections. This study aims to identify which teleconnections most significantly affect key biophysical processes in South America's two largest biomes: The Amazon and Cerrado.

Comparative study of a commercial formula containing natural antimicrobials versus oral cephalexin or topical chlorhexidine-miconazole therapies for treating superficial pyoderma in dogs.

Background: Chronic and recurrent pyoderma in dogs is driving a growing interest in natural antimicrobial products that offer minimal adverse effects and avoid antibiotic resistance.

Objectives: Evaluate the safety and efficacy of dermatological products with antimicrobial peptides and plant extracts, comparing them to chlorhexidine + miconazole and cephalexin therapy for superficial pyoderma in dogs.

Materials And Methods: Forty-five dogs with superficial pyoderma underwent clinical, cytopathological and microbiological diagnosis, and were randomly assigned to Group 1 (G1) treated with shampoo (two weekly baths) and lotion (twice daily on the affected areas) containing natural antimicrobials; Group 2 (G2) treated with two weekly baths using a therapeutic shampoo containing 2% chlorhexidine and 2.

Effect of fructooligosaccharides in full-hydrated lactic acid bacteria membrane models during thermal stress: A molecular simulation study.

Fructooligosaccharides (FOS) are a promising choice for cryoprotection of lactic acid bacteria (LAB). However, the mechanism by which this protection takes place is not well understood. Molecular simulation is a key tool for gathering insights into complex physicochemical problems like this.