Significance of intracytoplasmic crystalline inclusions in plasma cells - a review with case discussion.

Dense lymphoplasmacytic infiltrate in tissues pose diagnostic challenge to pathologists. Presence of intracytoplasmic crystalline inclusions in plasma cells has been strongly linked with B- cell lymphoproliferative disorders, although isolated reactive cases are also reported. We reviewed the literature and present clinical, morphological and immunohistochemical findings in a polyp of the cervix.

The accuracy of abnormal cytology report in breast fine needle aspiration alone and in combination with clinical and imaging findings - a hospital based five year study in Kuwait.

Background: Abnormal cytology report (C3 - C5) is routinely used as part of the triple assessment in diagnosis of malignant breast lesions. Its value has been questioned in recent years in view of an equivocal (C3, C4) results when compared with core biopsy. The aim of this study was to find the significance of abnormal report of cytology alone and in combination with clinical and image findings; and how accurately it helps in clinical decision making.

Mesenchymal chondrosarcoma of the thyroid -- a rare tumour at an unusual site.

We describe the light microscopic, immunohistochemical and ultrastructural features of the first case in the literature of a primary mesenchymal chondrosarcoma (MC) of the thyroid and discuss its differential diagnosis at unusual extraskeletal sites. A nodular lesion of the thyroid with no evidence of extrathyroid disease showed the bimorphic pattern and haemangiopericytoma-like areas typical of MC. In the undifferentiated areas, the cells were CD99 positive/CD117 negative, while the stroma showed focal positivity for alpha-inhibin.

Cellularity of lobular carcinoma and its relationship to false negative fine needle aspiration results.

Objective: To evaluate the cytocellularity and histocellularity of lobular carcinoma (LC) and the relationship to high false negative results of fine needle aspiration cytology (FNAC).

Study Design: In this retrospective study, cellularity was studied in 60 cases of classic LC, LC variants and lobular carcinoma in situ, comparing cytologic smears to their corresponding histologic sections. The cytologic smears were grouped into acellular, low, moderate and high categories, and the histologic sections were grouped into low, moderate and high categories.