Publications by authors named "T Akechi"
Article Synopsis
- Many cancer patients suffer from psychological distress and low quality of life during or after treatment, facing barriers to accessing support, making digital psychological interventions a potential solution.
- A comprehensive review of 136 randomized controlled trials identified effective digital interventions including cognitive behavioral therapy (CBT), health education, and virtual reality therapy (VRT), which significantly reduced psychological distress and improved quality of life compared to non-active controls.
- Digital CBT and VRT were particularly effective in addressing various issues like depression, anxiety, and fatigue, while CBT was the best for insomnia, and mindfulness-based interventions specifically reduced fear of cancer recurrence, highlighting the need for more high-quality trials in this area.
Article Synopsis
- Olanzapine is an atypical antipsychotic that helps prevent nausea and vomiting, particularly after highly emetogenic chemotherapy (HEC), but it can cause side effects like hyperglycemia and drowsiness.
- A systematic review and meta-analysis assessed the effectiveness of olanzapine combined with standard triplet antiemetic therapy compared to triplet therapy alone, focusing on outcomes like nausea control and adverse effects.
- Results showed that adding olanzapine significantly improved nausea and vomiting prevention in both acute and delayed phases with minimal adverse effects, indicating it can be beneficial for patients undergoing HEC.
Article Synopsis
- Research lacks a standardized multi-day antiemetic regimen for chemotherapy, making it difficult to assess efficacy and safety.
- A comprehensive search revealed no direct comparisons between multi-day and single-day antiemetic regimens, with variations in study quality and treatment protocols hindering robust analysis.
- Preliminary findings indicate that three-drug combination therapies, particularly using aprepitant, may outperform two-drug regimens; further research is needed to better define antiemetic approaches for multi-day chemotherapy.
Article Synopsis
- The study investigated the feasibility and effectiveness of a modified behavioral activation program aimed at helping individuals who have lost loved ones to cancer, specifically in reducing depressive symptoms.
- The program included a series of pre-interviews and seven 50-minute sessions, with participants showing high completion rates of 95% for the intervention and 90% for follow-up.
- Results indicated significant reductions in depression and anxiety symptoms, with large effect sizes measured three months post-intervention, suggesting that the program effectively supports bereaved individuals.
Aim: Spouses experience conflicting emotions when caring for partners with severe mental illnesses. They can have negative emotions while also regarding caregiving as positive and may develop a better marital relationship through the caregiving process. This study investigated factors affecting the negative and positive emotions of husbands and wives acting as caregivers of their spouses with severe mental illnesses.
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