Particular Chinese contributions to extracorporeal liver surgery.

Extracorporeal liver surgery (ELS), also known as liver autotransplantation, is a hybrid (cross-fertilized) surgery incorporating the technical knowledge from extreme liver and transplant liver surgeries, and recently became more embraced and popularized among leading centers. ELS could be summarized into three major categories, namely, ex-situ liver resection and autotransplantation (ELRA), ante-situm liver resection and autotransplantation (ALRA) and auxiliary partial liver autotransplantation (APLA). The successful development of ELS during the past 37 years is definitely inseparable from continuous efforts done by Chinese surgeons and researchers.

Upregulation of CD244 promotes CD8 T cell exhaustion in patients with alveolar echinococcosis and a murine model.

Background: In patients with alveolar echinococcosis (AE), CD8 T cells undergo functional exhaustion, which accelerates the malignant progression of AE. However, the role of inhibitory receptor CD244 in mediating CD8 T cell exhaustion remains elusive.

Methods: CD244 expression on exhausted CD8 T cells in the close liver tissue (CLT) of AE patients was analyzed using single-cell RNA sequencing data.

A special case of intrahepatic cholangiocarcinoma misdiagnosed as hepatic cystic echinococcosis.

Intrahepatic cholangiocarcinoma (iCCA) is a prevalent liver tumor that presents a diagnostic challenge due to its nonspecific symptoms, necessitating reliance on imaging techniques for accurate diagnosis. The similarity of imaging features with other liver diseases, such as hepatocellular carcinoma (HCC) and hepatic alveolar echinococcosis, often leads to confusion and misdiagnosis. In contrast, the distinct characteristics of hepatic cystic echinococcosis (HCE) result in fewer reported misdiagnoses.