Noise pollution is defined as any disturbing or unwanted sound that disrupts or harms human health or wildlife. Noise pollution can have profound effects on both human health and the environment. For humans, exposure to excessive noise levels has been linked to a range of health issues, including hearing damage, stress, and sleep disturbances.
View Article and Find Full Text PDFThis study assessed the growth, biomass, and carbon storage potential of four urban tree species-Pinus roxburghii, Broussonetia papyrifera, Jacaranda mimosifolia, and Eucalyptus camaldulensis-in Islamabad's greenbelts. Sampling was conducted using a quadrat method, covering five sites (F-9, G-8, H-8, I-8, Zero-Point), with 400 trees analyzed. Growth parameters such as diameter at breast height (DBH), height, aboveground biomass (AGB), aboveground carbon density (ACD), belowground carbon density (BCD), basal area (BA), and volume were measured.
View Article and Find Full Text PDFEur J Cancer
December 2024
Background: Most patients with small-cell lung cancer (SCLC) present with extensive-stage (ES) disease and have a poor prognosis despite achieving high initial response rates to platinum-based doublet chemotherapy. This study evaluated whether adding hydroxychloroquine (HCQ) to chemotherapy could improve outcomes.
Methods: This was a randomised multicentre phase II trial.
Aluminum chloride (AlCl), a known neurotoxic and Alzheimerogenic metal disrupts redox homeostasis which plays a pivotal role in pathophysiology of neurodegenerative disorders, particularly cognitive decline. The current study was designed to unveil the long-term neuroprotective outcomes and efficacy of CoQ10 and curcumin low dose (100 mg/kg each) combination in 18-months old geriatric male Balb/c mice subjected to AlCl-prompted memory derangements (200 mg/kg in water bottles) for 28 days. The neuroprotective properties driven by antioxidant mechanisms were assessed via observing cellular pathology in key-memory related brain regions including the cornuammonis (CA3 and DG) and cortex 2/3 layer.
View Article and Find Full Text PDFis a major producer of ochratoxin A (OTA), a highly toxic and carcinogenic mycotoxin found in various food and feed products. produces excessive amount of OTA under various water activity (a) conditions that occur during food and feed storage. The biosynthetic gene clusters associated with OTA production include , which plays a key role in controlling mycotoxin production in response to environmental conditions.
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