Publications by authors named "T Afsar"

Article Synopsis
  • - The study explores how variations in the PRKCG gene's non-coding regions, specifically the 3' and 5' UTRs, affect gene expression and post-transcriptional regulation, focusing on variants that could influence transcription factor binding and RNA interactions.
  • - Out of 419 UTR variants analyzed, 325 were deemed functionally significant, with specific variants linked to RNA binding proteins and regulatory mechanisms like histone modifications, as well as interactions with certain miRNAs in cancer.
  • - Findings reveal that these non-coding variants may alter mRNA structure and affect splicing efficiency, emphasizing their potential role in developing targeted therapies for cancer and other diseases.
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Background: The enhancement of ocular drug delivery is achieved by using biopolymer carriers in liquid ophthalmic preparations. Using natural polysaccharides to formulate ocular medications is attractive because they are economical and readily available. The primary goal of the study was to assess the safety and effectiveness of Tamarind seed polysaccharide (TSP)/Hyaluronic acid (HA) containing Rohto eye drops (TSP/HA drops) in alleviating the signs and symptoms of dry eye disease (DED) under dry environmental conditions using controlled environmental chamber (CEC).

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Over the past few decades, there has been increasing interest in using probiotics as an alternative to antibiotics. Researchers have conducted studies to investigate bacterial strains for their probiotic potential. Like other animals, fish also have several bacterial strains in their gut that possess probiotic properties, although this is limited to Bacillus species.

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