Exploring the Long-Term Tissue Accumulation and Excretion of 3 nm Cerium Oxide Nanoparticles after Single Dose Administration.

Nanoparticle (NP) pharmacokinetics significantly differ from traditional small molecule principles. From this emerges the need to create new tools and concepts to harness their full potential and avoid unnecessary risks. Nanoparticle pharmacokinetics strongly depend on size, shape, surface functionalisation, and aggregation state, influencing their biodistribution, accumulation, transformations, and excretion profile, and hence their efficacy and safety.

[The COVID-19: pandemic, vaccination, social dispositions of Russians].

The article describes, on the basis of the results of content analysis of posts and comments in social networks, the actual situation with coronavirus infection including its overcoming, security maintaining, possibility of risks and threats occurrence and acceptance/refusal of vaccination as well. The desk research technique was applied to analyze documents and publications of the WHO, live data from national resource www.стопкоронавирус.

[IMPLICATIONS OF THE FIRST WAVE OF COVID-19 FOR SMALL BUSINESSES: SOCIOLOGICAL ASSESSMENT].

Statement of the research problem. In the context of the coronavirus pandemic, small businesses have been exposed to serious risks, since their viability primarily depends on the consumer demand of the population, which in turn has declined sharply in these force majeure circumstances. Small businesses are either waiting for the lifting of restrictive measures, or they are counting on state support, or they are looking for other ways out of the current situation in order to preserve jobs, the level of income of employees, remain on the market and ensure the supply of vital goods and services to the population.

[The social factors increasing healthy life longevity (according sociological surveys materials)].

The article discusses the main social factors that can positively effect on increasing the longevity of healthy life in the elderly. The main principles are based on the results of applied studies carried out by the authors in Moscow, Kursk, Velikiy Novgorod and Simferopol in 2019-2020. The respondents were both the elderly themselves and the specialists providing them social services support.

[The physical activity and sport in life of elder generation of Russian cities].

The article is devoted to implementation of state policy of increasing duration of healthy life and active longevity of population through involvement of the elderly into sport and physical activity. The article is based on the results of focus group discussions of respondents aged 60 years and older. The interest and personal involvement of the elderly in sport and physical activity, including corresponding personal motivation and attitude.