Publications by authors named "T A Willis"
Renewal of the catecholamine-secreting chromaffin cell population of the adrenal medulla is necessary for physiological homeostasis throughout life. Definitive evidence for the presence or absence of an adrenomedullary stem cell has been enigmatic. In this work, we demonstrate that a subset of sustentacular cells endowed with a support role, are in fact adrenomedullary stem cells.
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- Paralabral cysts in the shoulder often develop due to issues like labral tears and can cause nerve compression, leading to muscle weakness and limited movement.
- Traditional treatment involves MRI diagnosis, surgical repairs, and cyst removal, but less invasive methods such as ultrasound-guided cyst aspiration are emerging as viable alternatives.
- A case study of a patient with a paralabral cyst showed that ultrasound-guided aspiration led to complete symptom relief and recovery without complications, highlighting its potential as a patient-friendly option compared to surgery.
Background: The need for effective non-pharmaceutical infection prevention measures such as contact tracing in pandemics remains in care homes, but traditional approaches to contact tracing are not feasible in care homes. The CONTACT intervention introduces Bluetooth-enabled wearable devices (BLE wearables) as a potential solution for automated contact tracing. Using structured reports and reports triggered by positive COVID-19 cases in homes, we fed contact patterns and trends back to homes to support better-informed infection prevention decisions and reduce blanket application of restrictive measures.
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- - Selective IgA deficiency (SIgAD) is the most common type of inherited immune disorder, but previous studies have struggled to find specific genetic variants due to small sample sizes.
- - Researchers conducted a meta-analysis of existing Genome-Wide Association Studies (GWAS), discovering four new common genetic variants linked to SIgAD and confirming connections to genes associated with other inherited immune disorders.
- - By analyzing the genetic links between SIgAD, serum IgA levels, asthma, and rheumatoid arthritis, the study identified an additional 18 genetic variants, raising the total to 27 and supporting the idea that SIgAD has a complex genetic basis.