[Hypofractionated radiation therapy for localized prostate cancer (first experience)].

This paper presents a study of 74 prostate cancer patients divided into 2 groups (study group and comparison group). The comparison group patients (n=50) were treated with radiation therapy in standard fractionated mode, while study group patients (n=24) underwent hypofractionated radiation therapy (STD 7.5 Gy; TTD 37.

Experimental study on the efficacy of the drug Brizantin in the model of nicotine dependence.

We estimated the efficacy of Brizantin preparation in suppressing nicotine dependence in rats. It was shown that nicotine-dependent rats in the situation of choice between the chamber with smoke or the chamber with food more frequently entered the chamber with tobacco smoke and stayed there longer. The rats that received Brizantin demonstrated significantly fewer visits to the chamber with smoke and spent there less time.

Experimental study of the effects of Dietressa, a new weight-reducing drug.

The capacity of a new drug containing ultra-low doses of antibodies to cannabinoid receptor type 1 (Dietressa) to reduce body weight gain in mice on a high-calorie diet was evaluated, possible mechanisms of drug action were analyzed, and its safety (abuse potential in the reaction of self-stimulation) was evaluated. Dietressa was not inferior to sibutramine in reducing body weight gain in mice and exhibited no abuse potential.

[Determination of the mutagenic potential of inorganic compounds of some heavy metals].

The authors determined the mutagenic potential of inorganic compounds, such as tungsten, molybdenum, lead, and copper, as well as waste of a tungsten-molybdenum industrial complex engaged in the exploitation of tungsten and molybdenum deposits, and environmental components, by using a plant test system and species of wild flora. They were shown to be suitable for the determination of genotoxicity of the environment polluted with heavy metals.

[Antibiotic susceptibility of isolates from blood of patients in intensive care units of emergency medical service].

The microbiological tests of 769 blood samples from 220 patients, treated in 4 intensive care units of the N.V. Sklifosovsky Research Institute for Emergency Medical Service within a period from January 2009 to June 2010, were analysed.