[Moyamoya disease].

Moyamoya syndrome is a rare chronic progressive disease of brain vessels in which certain arteries in the brain are constricted. During the disease a collateral circulation develops around the blocked vessels to compensate for the blockage, and on angiography these collateral vessels have the appearance of a "puff of smoke". Moyamoya syndrome is extremely rare disease, especially outside of Japan We describe a clinical case of a 27-year-old patient from Tomsk with Moyamoya disease.

[Mechanisms of DNA repair disorders in human cells. Genome instability in lymphocytes of patients with myopathy related to DNA repair disorders].

Increased level of cytogenetic damages was observed in lymphocytes of 10 patients with muscular dystrophy (Duchenne, Erba, Landuzi--Degerin). Analysis of DNA repair synthesis revealed inhibition of this process in lymphocytes of 10 patients observed. On the other hand, decreased reactivation of vaccinia virus and increased level of virus mutagenesis induced by 4-nitroquinoline-1-oxide and bleomycin was noted in the experiments with lymphocytes of 3 patients observed.

[Bound immunoglobulins and immune complexes in the thymus of myopathy patients].

Profound changes in epithelial and lymphoid tissues were detected by the immunofluorescent technique in the thymus of myopathy patients. The characteristic immunomorphological manifestation indicating injuries to the thymic epithelial tissue is the sedimentation of IgG, IgA and complement in basal membranes and in the cytoplasm of adjacent poorly differentiated epithelial cells. Another remarkable sign of the changes in the thymic epithelial tissue during the disease is a sharply marked cystic degeneration of Hassall bodies, eventuating in the sedimentation of keratinized material in the internal environment of the organ.